Papillomavirus الأعراض والأسباب - مايو كلينك 1

Papillomavirus Papillomavirus (HPV)

Recent developments in its causes, diagnosis, treatment and prevention

Professor Samir Samurai

Dubai Healthcare City

Human papillomavirus (HPV) is a virus that belongs to the PAPOVA group. This virus, which contains DNA, is spread by contact between the skin, especially during foreplay or sexual practice of any kind. Global statistics Thirty million people a year worldwide are infected with the virus in the sexual region alone, and six million new infections occur every year in the United States and eight hundred thousand in Europe, and the prevalence of HIV infection annually in women of all ages (% 26.8) while the number of women is increasing The incidence of infection is estimated annually among women between the ages of twenty and twenty four (44.8%).

There are 100 species of this virus, and the incidence of the two types (11, 6) is the most common and non-components of tumors and is a human papillomavirus of low risk, and the incidence of these human papillomavirus in the sexual region as well as in the respiratory system also, Human papillomavirus high risk is due to infection of the species (16, 18) in addition to the species (31,33,35,39,45,51,52,56,58,66,68,69,73,82), and that its presence is a person In the cells of malignant tumors in women in the cervix or vagina or vagina and the latter includes (labia, large and small labia, pubic and pubic (16, 18) may lead to cervical cancer by 70%, and that twelve thousand new infections of this cancer from infection of these two types of virus are diagnosed annually in the United States, And that unfortunately four thousand women are infected each year as a result of this, knowing that the incidence of men's penile cancer, and the incidence of cancer of the exit of men and women may be caused by both types of virus (16, 18) as well as may be caused by other types of high-risk mentioned Previously.

Risk factors:

There are reasons that lead to the risk of infection with HIV in the case of sexual partner is:

Sexual practice without protective.

Women taking contraceptives.

Smoking: Recently, research and clinical studies have shown that one of the factors leading to this virus is smoking, because it leads to an increase in the percentage of dysplasia in the sexual area and then to the incidence of malignant tumors in the genitals of men and women.

Immune suppression

Sexually transmitted diseases (STD).

Multiple sexual partners.

How to form the thorns after infection with the virus:

(6, 11), 16 (18) or other species mentioned above, causing the formation and growth of thymus in the external sexual area after a person has been subjected to microscopic abrasion during the sexual process, which leads to the penetration of the virus into the cells of the sexual area The period of papillomavirus after the infection is two to three months, and the presence of this virus after infection in the cervix, vagina, urethra, or exit, or mucous membranes in the mouth and nose, Infection through sexual intercourse However, the infection of the ears outside the exit may be due to contact with the skin of the sexual partner infected with 

the virus.

Most of these infections may be without symptoms, but this may cause rheumatism in some patients with pain, or heartburn, or itching, or local bleeding in the area of ​​the same.

There are symptoms that may be encountered by women infected with the virus, especially vaginal itching or painful discharge, but generally symptoms in patients with the first virus is the emergence of papillomavirus tumors in the genital area or sexual, and is initially a small thrombosis spread in men The area of ​​the scrotum, the perineum, the penis, or the outer urethra, and spreads to the woman in the vulva (vagina) or vagina or cervix.

The latency period of the virus (the period from the first day of the infection to the onset of symptoms, including thorns in the genital area or nationality and may extend from three weeks to eight months.

Diagnosis:

Clinical examination of this viral disease usually begins with the examination of the sexual and reproductive region and the search for papillomatous thalamus tumors by the magnifying glass (5X). To determine the type and seriousness of the oxalus, it is recently performed by a swab taken from the thymus surface to diagnose the DNA sequence and type of HPV in the polymerase chain reaction (PCR), and sometimes the patient must undergo laboratory testing for modern virus detection In the blood by neutralizing the Pseudovirion - Based Neutralization Assay if the PCR scan does not diagnose the HPV infection.

the cure:

Clinical and clinical findings of global epidemiological diseases have shown that there is a common factor between HIV infection (16,18) and cervical cancer partner (cervical cancer). Since HPV is one of the most common sexually transmitted diseases in men and women, At the same time, the high incidence of infection within the epithelial epithelial cells in the sexual area, it is also possible that the man infected with the virus to the incidence of cancer of the penis or cancer of the urethra, and the infected woman in addition to cervical cancer to the vaginal cancer, or cancer a thousand C, while exposure to the injury of the director of cancer because it is not to undergo treatment for early tooth wart and to undergo HIV prevention by vaccination against this infection or recurrence.

As for the treatment of modern and effective at present is the removal of laser erythema under local anesthesia. In the case of infection in the external urethral or internal urethra, or the vicinity of the exit, this is examined clinically and laboratory as stated in advance carefully and warned, but in case of suspected infection in the internal urethra The visual examination of the urethra and bladder should be performed prior to treatment of any infection of the viral wolves externally.

A few years ago we were able to globally and locally - and thank God - from the eradication of these thorns and tumors resulting by evaporating laser beam with a success rate of 72%, and the rate of growth and return again by 28%, and there are recent clinical studies indicate the success of local treatment in the case Back to the incidence of ulcers despite laser removal, especially in women. The most commonly used is the Imiquimod ointment. This drug leads to cellular adaptation within the human papillomavirus leading to the secretion of a cytokine in the cell, thereby reducing the reproduction of the virus within it, where it is then eliminated. Women are 77% and men are 40%.

The new vaccines have a four-fold immunization efficiency against these viruses, which contain L1, the largest clonal protein of the virus. This technology is made in the way of RNA sequestration to obtain similar parts of the virus by treating it in this way to create a papillomavirus- To be a quadrivalent vaccine against the virus, and the first vaccine is commercially called Gardasil.

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